Replicate supports TLS 1.2 or later. However, support for TLS 1.3 is dependent on the Replicate server you choose to work with.
The native Replicate server listener (port 3552) supports TLS 1.2 or later. However, if you work against the Replicate UI server (which uses the OS HTTP stack), you will need to make sure the OS HTTP includes support for TLS 1.2 and later. Information pertaining to this should be found on the OS vendor site.
For more information on Replicate server configurations, see Qlik Replicate UI server configurations.